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À partir d’avant-hierArs Technica

Secrets of the Octopus takes us inside the world of these “aliens on Earth”

A Day octopus octopus cyanea) parachutes her web over a coral head while Dr. Alex Schnell observes.

Enlarge / A Day octopus (Octopus cyanea) named Scarlet parachutes her web over a coral head while Dr. Alex Schnell observes. (credit: National Geographic/Disney/Craig Parry)

With Earth Day fast approaching once again, it's time for another new documentary from National Geographic and Disney+:  Secrets of the Octopus. It's the third in what has become a series, starting with the remarkable 2021 documentary Secrets of the Whales (narrated by Sigourney Weaver) and 2023's Secrets of the Elephants (Natalie Portman as narrator). James Cameron served as producer on all three.

Secrets of the Octopus is narrated by Paul Rudd. Per the official synopsis:

Octopuses are like aliens on Earth: three hearts, blue blood and the ability to squeeze through a space the size of their eyeballs. But there is so much more to these weird and wonderful animals. Intelligent enough to use tools or transform their bodies to mimic other animals and even communicate with different species, the secrets of the octopus are more extraordinary than we ever imagined.

Each of the three episodes focuses on a specific unique feature of these fascinating creatures: "Shapeshifters," "Masterminds," and "Social Networks." The animals were filmed in their natural habitats over 200 days and all that stunning footage is accompanied by thoughtful commentary by featured scientists.  One of those scientists is Dr. Alex Schnell,  a native Australian and self described storytelling who has worked at Macquarie University, the University of Cambridge, and the Marine Biological Laboratory, among other institutions. Her research focuses on the intelligence of marine animals, particularly cuttlefish and octopuses.

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TSMC’s $65 billion bet still leaves US missing piece of chip puzzle

President Biden speaking at the official opening of TSMC’s first Arizona fabrication plant in December 2022. The Taiwanese chipmaker plans to start manufacturing 2-nanometer chips in the US in 2028.

Enlarge / President Biden speaking at the official opening of TSMC’s first Arizona fabrication plant in December 2022. The Taiwanese chipmaker plans to start manufacturing 2-nanometer chips in the US in 2028. (credit: Caitlin O’Hara/Bloomberg via Getty)

Taiwan Semiconductor Manufacturing Company’s decision to bring its latest technology to America is a big step forward for US President Joe Biden’s quest for security in the vital tech supply chain—but still leaves Washington short of being able to completely produce the most complex chips in the US.

The world’s biggest chipmaker by sales must also pull off an intricate balancing act as it steps up its US presence, satisfying customers such as Nvidia without damaging its highly profitable business model, which has underpinned the development of the global semiconductor industry for more than 30 years.

TSMC’s planned $65 billion of investments in Arizona are part of a construction race in the US that involves other global chipmakers such as Samsung and Intel, which are also taking big subsidies from Washington.

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Will there be a Dune: Part Three? Yes… with caveats on timing

Legendary Pictures has confirmed that it plans to make <em>Dune: Part Three</em> with director Denis Villeneuve.

Enlarge / Legendary Pictures has confirmed that it plans to make Dune: Part Three with director Denis Villeneuve. (credit: YouTube/Warner Bros.)

Dune: Part Two is still raking in the moolah at the box office, and deservedly so. But judging by my various feeds, fans are already swooning over the prospect of director Denis Villeneuve extending his vision into a trilogy by adapting Frank Herbert's 1969 sequel, Dune Messiah, for the next installment. Will there be a Dune: Part Three? Most signs currently point to yes, with a couple of caveats. Exactly how soon we'll be seeing a return to Arrakis depends a lot on Villeneuve.

Variety confirmed that Legendary Pictures is working with the director on developing Dune: Part Three, although it remains unclear from the wording of the plethora of news items whether the project has officially been greenlit. ("Development" can mean a lot of things.) Naturally, the studio is eager, as are we: the film is the biggest hit of 2024 thus far, with global earnings of $630 million (although the hotly anticipated Deadpool and Wolverine this summer might give it a run for its money).

That confirmation sent fresh frissons of excitement across the Internet, although Villeneuve had been talking about the prospect as far back as September 2021. Those plans always depended on the success of Part Two, and that hurdle has obviously been cleared. By August 2023, the director was on record saying there were "words on paper" for a third film. And we learned just last month that composer Hans Zimmer was already working on the score for Dune: Part Three.

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The best robot to search for life could look like a snake

Image of two humans sitting behind a control console dressed in heavy clothing, while a long tube sits on the ice in front of them.

Enlarge / Trying out the robot on a glacier. (credit: NASA/JPL-Caltech)

Icy ocean worlds like Europa or Enceladus are some of the most promising locations for finding extra-terrestrial life in the Solar System because they host liquid water. But to determine if there is something lurking in their alien oceans, we need to get past ice cover that can be dozens of kilometers thick. Any robots we send through the ice would have to do most of the job on their own because communication with these moons takes as much as 155 minutes.

Researchers working on NASA Jet Propulsion Laboratory's technology development project called Exobiology Extant Life Surveyor (EELS) might have a solution to both those problems. It involves using an AI-guided space snake robot. And they actually built one.

Geysers on Enceladus

The most popular idea to get through the ice sheet on Enceladus or Europa so far has been thermal drilling, a technique used for researching glaciers on Earth. It involves a hot drill that simply melts its way through the ice. “Lots of people work on different thermal drilling approaches, but they all have a challenge of sediment accumulation, which impacts the amount of energy needed to make significant progress through the ice sheet,” says Matthew Glinder, the hardware lead of the EELS project.

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Microsoft blamed for “a cascade of security failures” in Exchange breach report

Microsoft logo on a wide sign

Enlarge (credit: Getty Images)

A federal Cyber Safety Review Board has issued its report on what led to last summer's capture of hundreds of thousands of emails by Chinese hackers from cloud customers, including federal agencies. It cites "a cascade of security failures at Microsoft" and finds that "Microsoft's security culture was inadequate" and needs to adjust to a "new normal" of cloud provider targeting.

The report, mandated by President Biden in the wake of the far-reaching intrusion, details the steps that Microsoft took before, during, and after the breach and in each case finds critical failure. The breach was "preventable," even though it cites Microsoft as not knowing precisely how Storm-0558, a "hacking group assessed to be affiliated with the People's Republic of China," got in.

"Throughout this review, the board identified a series of Microsoft operational and strategic decisions that collectively points to a corporate culture that deprioritized both enterprise security investments and rigorous risk management," the report reads.

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George Carlin estate forces “AI Carlin” off the Internet for good

The original YouTube thumbnail for Dudesy's Carlin special shows an AI-generated comedian sporting Carlin's signature gray ponytail look.

Enlarge / The original YouTube thumbnail for Dudesy's Carlin special shows an AI-generated comedian sporting Carlin's signature gray ponytail look. (credit: Carlin estate vs. Dudesy lawsuit)

The George Carlin estate has settled its lawsuit with Dudesy, the podcast that purportedly used a "comedy AI" to produce an hour-long stand-up special in the style and voice of the late comedian.

Dudesy's "George Carlin: Dead and Loving It" special, which was first uploaded in early January, gained hundreds of thousands of views and plenty of media attention for its presentation as a creation of an AI that had "listened to all of George Carlin’s material... to imitate his voice, cadence and attitude as well as the subject matter I think would have interested him today." But even before the Carlin estate lawsuit was filed, there were numerous signs that the special was not actually written by an AI, as Ars laid out in detail in a feature report.

Shortly after the Carlin estate filed its lawsuit against Dudesy in late January, a representative for Dudesy host Will Sasso told The New York Times that the special had actually been "completely written by [Dudesy co-host] Chad Kultgen."

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Billie Eilish, Pearl Jam, 200 artists say AI poses existential threat to their livelihoods

Billie Eilish attends the 2024 Vanity Fair Oscar Party hosted by Radhika Jones at the Wallis Annenberg Center for the Performing Arts on March 10, 2024 in Beverly Hills, California.

Enlarge / Billie Eilish attends the 2024 Vanity Fair Oscar Party hosted by Radhika Jones at the Wallis Annenberg Center for the Performing Arts on March 10, 2024, in Beverly Hills, California. (credit: Getty Images)

On Tuesday, the Artist Rights Alliance (ARA) announced an open letter critical of AI signed by over 200 musical artists, including Pearl Jam, Nicki Minaj, Billie Eilish, Stevie Wonder, Elvis Costello, and the estate of Frank Sinatra. In the letter, the artists call on AI developers, technology companies, platforms, and digital music services to stop using AI to "infringe upon and devalue the rights of human artists." A tweet from the ARA added that AI poses an "existential threat" to their art.

Visual artists began protesting the advent of generative AI after the rise of the first mainstream AI image generators in 2022, and considering that generative AI research has since been undertaken for other forms of creative media, we have seen that protest extend to professionals in other creative domains, such as writers, actors, filmmakers—and now musicians.

"When used irresponsibly, AI poses enormous threats to our ability to protect our privacy, our identities, our music and our livelihoods," the open letter states. It alleges that some of the "biggest and most powerful" companies (unnamed in the letter) are using the work of artists without permission to train AI models, with the aim of replacing human artists with AI-created content.

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Medicare forced to expand forms to fit 10-digit bills—a penny shy of $100M

Par : Beth Mole
High angle close-up view still life of an opened prescription bottles with pills and medication spilling onto ae background of money, U.S. currency with Lincoln Portrait.

Enlarge (credit: Getty | YinYang)

In a disturbing sign of the times, Medicare this week implemented a change to its claims-processing system that adds two extra digits to money amounts, expanding the fields from eight digits to 10. The change now allows for billing and payment totals of up to $99,999,999.99, or a penny shy of $100 million.

In a notice released last month, the Centers for Medicare & Medicaid Services (CMS) explained the change, writing, "With the increase of Part B procedures/treatments exceeding the $999,999.99 limitation, CMS is implementing the expansion of display screens for monetary amount fields related to billing and payment within [the Fiscal Intermediary Shared System (FISS)] to accept and process up to 10 digits ($99,999,999.99)."

The FISS is the processing system used by hospitals and doctors' offices to process Medicare claims.

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Pornhub prepared to block Florida if child safety law takes effect

Pornhub prepared to block Florida if child safety law takes effect

Enlarge (credit: Aurich Lawson | Getty Images)

This week, Florida made headlines after passing HB 3, a law banning children under 14 from accessing social media without parental consent.

Much less attention was given to another requirement under the law obligating "pornographic or sexually explicit websites" to "use age verification to prevent minors from accessing sites that are inappropriate for children," as Republican Florida Governor Ron DeSantis explained the law in a statement.

But Pornhub's parent company, Aylo, has taken notice, with a spokesperson confirming to Ars that "we are aware of the passage into law of HB 3 in Florida, which unfortunately fails to protect minors online."

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“We’ve done our job”: Baldur’s Gate 3 devs call off DLC and step away from D&D

Karlach, the tiefling barbarian, infernal heart glowing, axe at her back.

Enlarge / Sometimes your infernal-engine-powered heart just isn't in it. (credit: Larian Studios/Hasbro)

Swen Vincke, director of the colossal entity that is Baldur's Gate 3, is not leaving the door open to future expansions of that already fully packed game.

At this week's Game Developer's Conference (GDC), Vincke made it clear during a talk and in interviews that Larian Studios is not going to make any major new content for Baldur's Gate 3 (BG3)—nor start work on Baldur's Gate 4, nor make anything, really, inside the framework of Dungeons & Dragons' Fifth Edition (5e).

Not that Vincke or his team are bitter. Their hearts just aren't in it. They had actually started work on BG3 downloadable content and gave some thought to Baldur's Gate 4, Vincke told IGN. "But we hadn’t really had closure on BG3 yet and just to jump forward on something new felt wrong." On top of that, the team had new ideas that didn't fit D&D 5e, which "is not an easy system to put into a video game," Vincke said.

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Report: Superconductivity researcher found to have committed misconduct

Image of a large lawn, with a domed building flanked by trees and flagpoles at its far end.

Enlarge / Rush Rhees Library at the University of Rochester. (credit: Kickstand)

We've been following the saga of Ranga Dias since he first burst onto the scene with reports of a high-pressure, room-temperature superconductor, published in Nature in 2020. Even as that paper was being retracted due to concerns about the validity of some of its data, Dias published a second paper claiming a similar breakthrough: a superconductor that works at high temperatures but somewhat lower pressures. Shortly afterward, that got retracted as well.

On Wednesday, the University of Rochester, where Dias is based, announced that it had concluded an investigation into Dias and found that he had committed research misconduct. (The outcome was first reported by The Wall Street Journal.)

The outcome is likely to mean the end of Dias' career, as well as the company he founded to commercialize the supposed breakthroughs. But it's unlikely we'll ever see the full details of the investigation's conclusions.

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This stretchy electronic material hardens upon impact just like “oobleck”

This flexible and conductive material has “adaptive durability,” meaning it gets stronger when hit.

Enlarge / This flexible and conductive material has “adaptive durability,” meaning it gets stronger when hit. (credit: Yue (Jessica) Wang)

Scientists are keen to develop new materials for lightweight, flexible, and affordable wearable electronics so that, one day, dropping our smartphones won't result in irreparable damage. One team at the University of California, Merced, has made conductive polymer films that actually toughen up in response to impact rather than breaking apart, much like mixing corn starch and water in appropriate amounts produces a slurry that is liquid when stirred slowly but hardens when you punch it (i.e., "oobleck"). They described their work in a talk at this week's meeting of the American Chemical Society in New Orleans.

"Polymer-based electronics are very promising," said Di Wu, a postdoc in materials science at UCM. "We want to make the polymer electronics lighter, cheaper, and smarter. [With our] system, [the polymers] can become tougher and stronger when you make a sudden movement, but... flexible when you just do your daily, routine movement. They are not constantly rigid or constantly flexible. They just respond to your body movement."

As we've previously reported, oobleck is simple and easy to make. Mix one part water to two parts corn starch, add a dash of food coloring for fun, and you've got oobleck, which behaves as either a liquid or a solid, depending on how much stress is applied. Stir it slowly and steadily and it's a liquid. Punch it hard and it turns more solid under your fist. It's a classic example of a non-Newtonian fluid.

In an ideal fluid, the viscosity largely depends on temperature and pressure: Water will continue to flow regardless of other forces acting upon it, such as being stirred or mixed. In a non-Newtonian fluid, the viscosity changes in response to an applied strain or shearing force, thereby straddling the boundary between liquid and solid behavior. Stirring a cup of water produces a shearing force, and the water shears to move out of the way. The viscosity remains unchanged. But for non-Newtonian fluids like oobleck, the viscosity changes when a shearing force is applied.

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Entirely accurate 3D-printed Mac Plus built in these 29 painstaking steps

Booted Mac replica with MacPaint open,

Enlarge (credit: Kevin Noki)

Have you ever worked on a hobby project where modifying and compiling the source code for a Linux-based emulator was possibly the easiest and most straightforward part of the whole thing?

Kevin Noki really, really wanted a functioning Macintosh Plus, complete with a functioning, auto-ejecting disk drive that it could boot from. The German maker already had a Mac Plus (1Mb) from eBay, but it had both a busted power supply and floppy drive. Rather than carve out the busted Plus' one-of-a-kind internals and slap a Raspberry Pi in there like some DIY slacker, Noki went… a different path.

47 minutes and 25 seconds of a tour-de-force of modern maker technology.

Noki 3D-printed his own Macintosh, the "Brewintosh." I would like you to consider what you think that last sentence means and then wipe your expectations clean. I have watched the entire 48-minute journey of Noki's Brewintosh, which is both very soothing on some ASMR-adjacent gut level and also low-key maddening for the way it plays down all the individual accomplishments along the way. Any one of the Brewintosh's pieces would be my entire weekend, and my spouse would not enjoy my mood while I was sunk into it.

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NatGeo’s Photographer flips the lens to focus on visual storytellers

NatGeo's new series, Photographer, gives us a glimpse behind the lens.

National Geographic is justly renowned for its incredible photographs and eye-popping video footage, capturing all manner of natural marvels in gorgeous, jaw-dropping detail. Now the people behind those amazing shots are getting their moment in the spotlight with the documentary series Photographer.

If you've ever wanted to know more about what it's really like to be a NatGeo photographer, this series will take you behind the scenes as the photographers strive to meet the challenges and inevitable surprise obstacles to get that timeless shot. Each episode focuses on a different photographer, combining vérité footage with in-depth interviews and archival footage to help viewers see the world through their eyes—whether it be capturing a hummingbird in flight, chronicling a campaign against oil rigs in the Bahamas, or recording protests, rocket launches, tornadoes, or the behavior of whales, to name a few.

The exclusive clip above features photographer Anand Varma, who started out studying marine biology, intent on following in his father's footsteps as a scientist. But after taking a job as a camera assistant, he fell in love with photography and has carved out his own niche at the interface of science and art. His latest project is a photographic series centered on metamorphosis—in this case, trying to capture the formation and hatching of a chicken embryo on camera.

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Lawsuit opens research misconduct report that may get a Harvard prof fired

Image of a campus of red brick buildings with copper roofs.

Enlarge / Harvard's got a lawsuit on its hands. (credit: Glowimages)

Accusations of research misconduct often trigger extensive investigations, typically performed by the institution where the misconduct allegedly took place. These investigations are internal employment matters, and false accusations have the potential to wreck someone's career needlessly. As a result, most of these investigations are kept completely confidential, even after their completion.

But all the details of a misconduct investigation performed by Harvard University became public this week through an unusual route. The professor accused of misconduct, Francesca Gino, had filed a multi-million dollar lawsuit, targeting both Harvard and a team of external researchers who had accused her of misconduct. Harvard submitted its investigator's report as part of its attempt to have part of the suit dismissed, and the judge overseeing the case made it public.

We covered one of the studies at issue at the time of its publication. It has since been retracted, and we'll be updating our original coverage accordingly.

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Devs left with tough choices as Warner Bros. ends all Adult Swim Games downloads

A plucky, likable creature under the looming threat of consumption by an interconnected menacing force of nature in one of Adult Swim Games' titles.

Enlarge / A plucky, likable creature under the looming threat of consumption by an interconnected menacing force of nature in one of Adult Swim Games' titles. (credit: Adult Swim Games)

Warner Bros. Discovery seems set to remove at least 16 games from its Adult Swim Games subsidiary from games markets and has told the affected developers that it will not transfer the games back to them nor offer other means of selling them in the future.

Ars reported Wednesday on the plight of Small Radios Big Televisions, a Steam and PlayStation game made by a solo developer who received a notice from Warner Bros. Discovery (WBD) that it was "retiring" his game within 60 days.

In a comment on that Ars post, Matt Kain, developer of Adult Swim Games' Fist Puncher, noted that they had received the same "retired" notice from WBD. "When we requested that Warner Bros simply transfer the game over to our studio's Steam publisher account so that the game could stay active, they said no. The transfer process literally takes a minute to initiate (look up "Transferring Applications" in the Steamworks documentation), but their rep claimed they have simply made the universal decision not to transfer the games to the original creators," Kain wrote.

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Was F1 too boring? Watch these races instead

a man waves a checkered flag

Enlarge (credit: Getty Images)

Formula 1's 2024 season burst into action this past weekend at the Bahrain Grand Prix. The 10 teams had just spent three days conducting preseason testing at the Sakhir circuit, but Friday's qualifying session was the first time everyone left the sandbags in the garage. On Saturday, we got a true reflection of just how much of a gap there is between Max Verstappen in the Red Bull and the other 19 drivers.

The prospect of a third runaway championship for the Dutch driver will be too much for some fans to stomach, and social media is full of complaints from people who want to cancel their F1 subscriptions. Not everyone can find the excitement in a race for second place, after all. Luckily, F1 isn't the only game in town.

Check out Formula 2

Take this year's Formula 2 season, for example. As the name suggests, it's the feeder series for F1, a place for younger drivers to cut their teeth before (hopefully) moving up to the main attraction. Everyone uses the same car in F2, and for 2024, it's all-new. The car is built by Dallara, which also makes IndyCar's chassis, the Japanese Super Formula car, the Formula 3 car, and sports prototypes for Ferrari, Cadillac, and BMW. It's powered by a 3.4 L turbocharged V6 with around 620 hp (462 kW).

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India’s plan to let 1998 digital trade deal expire may worsen chip shortage

India’s plan to let 1998 digital trade deal expire may worsen chip shortage

Enlarge (credit: Narumon Bowonkitwanchai | Moment)

India's plan to let a moratorium on imposing customs duties on cross-border digital e-commerce transactions expire may end up hurting India's more ambitious plans to become a global chip leader in the next five years, Reuters reported.

It could also worsen the global chip shortage by spiking semiconductor industry costs at a time when many governments worldwide are investing heavily in expanding domestic chip supplies in efforts to keep up with rapidly advancing technologies.

Early next week, world leaders will convene at a World Trade Organization (WTO) meeting, just before the deadline to extend the moratorium hits in March. In place since 1998, the moratorium has been renewed every two years since—but India has grown concerned that it's losing significant revenues from not imposing taxes as demand rises for its digital goods, like movies, e-books, or games.

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Ala. hospital halts IVF after state’s high court ruled embryos are “children”

Par : Beth Mole
Nitrogen tanks holding tens of thousands of frozen embryos and eggs sit in the embryology lab at New Hope Fertility Center in New York City on December 20, 2017.

Enlarge / Nitrogen tanks holding tens of thousands of frozen embryos and eggs sit in the embryology lab at New Hope Fertility Center in New York City on December 20, 2017. (credit: Getty | Carolyn Van Houten)

The University of Alabama at Birmingham (UAB) health system is halting in vitro fertilization treatment in the wake of a ruling by the state's Supreme Court on Friday that deemed frozen embryos to be "children." The ruling opens up anyone who destroys embryos to liability in a wrongful death lawsuit, according to multiple media reports.

The announcement—the first facility to report halting IVF services—is the much-feared outcome of Friday's ruling, which was widely decried by reproductive health advocates.

"We are saddened that this will impact our patients' attempt to have a baby through IVF, but we must evaluate the potential that our patients and our physicians could be prosecuted criminally or face punitive damages for following the standard of care for IVF treatments," UAB said a statement to media. The statement noted that egg retrieval would continue but that egg fertilization and embryo development are now paused.

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Frozen embryos are “children,” according to Alabama’s Supreme Court

Par : Beth Mole
January 17, 2024, Berlin: In the cell laboratory at the Fertility Center Berlin, an electron microscope is used to fertilize an egg cell.

Enlarge / January 17, 2024, Berlin: In the cell laboratory at the Fertility Center Berlin, an electron microscope is used to fertilize an egg cell. (credit: Getty | Jens Kalaene)

The Alabama Supreme Court on Friday ruled that frozen embryos are "children," entitled to full personhood rights, and anyone who destroys them could be liable in a wrongful death case.

The first-of-its-kind ruling throws into question the future use of assisted reproductive technology (ART) involving in vitro fertilization for patients in Alabama—and beyond. For this technology, people who want children but face challenges to conceiving can create embryos in clinical settings, which may or may not go on to be implanted in a uterus.

In the Alabama case, a hospital patient wandered through an unlocked door, removed frozen, preserved embryos from subzero storage and, suffering an ice burn, dropped the embryos, destroying them. Affected IVF patients filed wrongful-death lawsuits against the IVF clinic under the state's Wrongful Death of a Minor Act. The case was initially dismissed in a lower court, which ruled the embryos did not meet the definition of a child. But the Alabama Supreme Court ruled that "it applies to all children, born and unborn, without limitation." In a concurring opinion, Chief Justice Tom Parker cited his religious beliefs and quoted the Bible to support the stance.

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DuckDuckGo’s browser adds encrypted, privacy-minded syncing and backup

Devices shown as synced between DuckDuckGo browsers

Enlarge (credit: DuckDuckGo)

DuckDuckGo keeps adding new features to its browser; and while these features are common in other browsers, DuckDuckGo is giving them a privacy-minded twist. The latest is a private, end-to-end encrypted syncing service. There's no account needed, no sign-in, and the company says it never sees what you're syncing.

Using QR codes and shortcodes, and a lengthy backup code you store somewhere safe, DuckDuckGo's browser can keep your bookmarks, passwords, "favorites" (i.e., new tab page shortcuts), and settings for its email protection service synced between devices and browsers.

DuckDuckGo points to Google's privacy policy for using its signed-in sync service on Chrome, which uses "aggregated and anonymized synchronized browsing data to improve other Google products and services." DuckDuckGo states that the encryption key for browser sync is stored only locally on your devices and that it lacks any access to your passwords or other data.

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Judge tosses Big Pharma suit claiming drug price negotiation is unconstitutional

Par : Beth Mole
Stephen Ubl, president and chief executive officer of Pharmaceutical Research and Manufacturers of America (PhRMA), speaks during a Bloomberg Live discussion in Washington, DC, on Tuesday, Sept. 19, 2017.

Enlarge / Stephen Ubl, president and chief executive officer of Pharmaceutical Research and Manufacturers of America (PhRMA), speaks during a Bloomberg Live discussion in Washington, DC, on Tuesday, Sept. 19, 2017. (credit: Getty | Andrew Harrer)

A federal judge in Texas dismissed a lawsuit Monday brought by a heavy-hitting pharmaceutical trade group, which argued that forcing drug makers to negotiate Medicare drug prices is unconstitutional.

The dismissal is a small win for the Biden administration, which is defending the price negotiations on multiple fronts. The lawsuit dismissed Monday is just one of nine from the pharmaceutical industry, all claiming in some way that the price negotiations laid out in the Inflation Reduction Act of 2022 are unconstitutional. The big pharmaceutical companies suing the government directly over the negotiations include Johnson & Johnson, Bristol Myers Squibb, Novo Nordisk, Merck, and AstraZeneca.

Last month, a federal judge in Delaware heard arguments from AstraZeneca's lawyers, which reportedly went poorly. AstraZeneca argued that Medicare's new power to negotiate drug prices violates the company's rights under the Fifth Amendment's due process clause. The forced negotiations deprive the company of “property rights in their drug products and their patent rights" without due process, AstraZeneca claimed. But Colm Connolly, chief judge of the US District Court of Delaware, was skeptical of how that could be the case, according to a Stat reporter who was present for the hearing. Connolly noted that AstraZeneca doesn't have to sell drugs to Medicare. "You’re free to do what you want," Connolly reportedly said. "You may not make as much money."

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Big Pharma spends billions more on executives and stockholders than on R&D

Par : Beth Mole
Big Pharma spends billions more on executives and stockholders than on R&D

Enlarge (credit: Senate HELP Committee)

When big pharmaceutical companies are confronted over their exorbitant pricing of prescription drugs in the US, they often retreat to two well-worn arguments: One, that the high drug prices cover costs of researching and developing new drugs, a risky and expensive endeavor, and two, that middle managers—pharmacy benefit managers (PBMs), to be specific—are actually the ones price gouging Americans.

Both of these arguments faced substantial blows in a hearing Thursday held by the Senate Committee on Health, Education, Labor and Pensions, chaired by Sen. Bernie Sanders (I-Vt.). In fact, pharmaceutical companies are spending billions of dollars more on lavish executive compensation, dividends, and stock buyouts than they spend on research and development (R&D) for new drugs, Sanders pointed out. "In other words, these companies are spending more to enrich their own stockholders and CEOs than they are in finding new cures and new treatments," he said.

And, while PBMs certainly contribute to America's uniquely astronomical drug pricing, their profiteering accounts for a small fraction of the massive drug market, Sanders and an expert panelist noted. PBMs work as shadowy middle managers between drugmakers, insurers, and pharmacies, setting drug formularies and consumer prices, and negotiating rebates and discounts behind the scenes. Though PBMs practices contribute to overall costs, they pale compared to pharmaceutical profits.

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Report: Sam Altman seeking trillions for AI chip fabrication from UAE, others

WASHINGTON, DC - JANUARY 11: OpenAI Chief Executive Officer Sam Altman walks on the House side of the U.S. Capitol on January 11, 2024 in Washington, DC. Meanwhile, House Freedom Caucus members who left a meeting in the Speakers office say that they were talking to the Speaker about abandoning the spending agreement that Johnson announced earlier in the week. (Photo by Kent Nishimura/Getty Images)

Enlarge / OpenAI Chief Executive Officer Sam Altman walks on the House side of the US Capitol on January 11, 2024, in Washington, DC. (Photo by Kent Nishimura/Getty Images) (credit: Getty Images)

On Thursday, The Wall Street Journal reported that OpenAI CEO Sam Altman is in talks with investors to raise as much as $5 trillion to $7 trillion for AI chip manufacturing, according to people familiar with the matter. The funding seeks to address the scarcity of graphics processing units (GPUs) crucial for training and running large language models like those that power ChatGPT, Microsoft Copilot, and Google Gemini.

The high dollar amount reflects the huge amount of capital necessary to spin up new semiconductor manufacturing capability. "As part of the talks, Altman is pitching a partnership between OpenAI, various investors, chip makers and power providers, which together would put up money to build chip foundries that would then be run by existing chip makers," writes the Wall Street Journal in its report. "OpenAI would agree to be a significant customer of the new factories."

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US funds $5B chip effort after lagging on semiconductor innovation

US President Joe Biden speaks before signing the CHIPS and Science Act of 2022.

Enlarge / US President Joe Biden speaks before signing the CHIPS and Science Act of 2022. (credit: Chip Somodevilla / Staff | Getty Images North America)

The Biden administration announced investments Friday totaling more than $5 billion in semiconductor research and development intended to re-establish the US as a global leader manufacturing the "next generation of semiconductor technologies."

Through sizeable investments, the US will "advance US leadership in semiconductor R&D, cut down on the time and cost of commercializing new technologies, bolster US national security, and connect and support workers in securing good semiconductor jobs," a White House press release said.

Currently, the US produces "less than 10 percent" of the global chips supply and "none of the most advanced chips," the White House said. But investing in programs like the National Semiconductor Technology Center (NSTC)—considered the "centerpiece" of the CHIPS and Science Act's four R&D programs—and training a talented workforce could significantly increase US production of semiconductors that the Biden administration described as the "backbone of the modern economy."

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Biogen dumps dubious Alzheimer’s drug after profit-killing FDA scandal

Par : Beth Mole
Multistory glass office building.

Enlarge / The exterior of the headquarters of biotechnology company Biogen in Cambridge, Massachusetts. (credit: Getty | Boston Globe)

Biotechnology company Biogen is abandoning Aduhelm, its questionable Alzheimer's drug that has floundered on the market since its scandal-plagued regulatory approval in 2021 and brow-raising pricing.

On Wednesday, the company announced it had terminated its license for Aduhelm (aducanumab) and will stop all development and commercialization activities. The rights to Aduhelm will revert back to Neurimmune, the Swiss biopharmaceutical company that discovered it.

Biogen will also end the Phase 4 clinical trial, ENVISION, that was required by the Food and Drug Administration to prove Biogen's claims that Aduhelm is effective at slowing progression of Alzheimer's in its early stages—something two Phase 3 trials failed to do with certainty.

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Air pollution from Canada’s tar sands is much worse than we thought

Aerial Views Of Oil Sands Operations

Enlarge / Aerial view of the Athabasca oil sands near Fort McMurray, Alberta, Canada. (credit: Bloomberg Creative via Getty)

Canada’s tar sands have gained infamy for being one of the world’s most polluting sources of oil, thanks to the large amounts of energy and water use required for their extraction. A new study says the operations are also emitting far higher levels of a range of air pollutants than previously known, with implications for communities living nearby and far downwind.

The research, published Thursday in Science, took direct measurements of organic carbon emissions from aircraft flying above the tar sands, also called oil sands, and found levels that were 20 to 64 times higher than what companies were reporting. Total organic carbon includes a wide range of compounds, some of which can contribute directly to hazardous air pollution locally and others that can react in the atmosphere to form small particulate matter, or PM 2.5, a dangerous pollutant that can travel long distances and lodge deep in the lungs.

The study found that tar sands operations were releasing as much of these pollutants as all other human-made sources in Canada combined. For certain classes of heavy organic compounds, which are more likely to form particulates downwind, the concentrations were higher than what’s generally found in large metropolises like Los Angeles.

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Dungeons & Dragons turns 50 this year, and there’s a lot planned for it

The three rulebooks for "fantastic medieval wargames" that started it all, released at some point in late January 1974, as seen in <a href="https://bookshop.org/p/books/dungeons-dragons-art-arcana-a-visual-history-sam-witwer/7280339"><em>Dungeons & Dragons Art & Arcana: A Visual History</em></a>.

Enlarge / The three rulebooks for "fantastic medieval wargames" that started it all, released at some point in late January 1974, as seen in Dungeons & Dragons Art & Arcana: A Visual History. (credit: Wizards of the Coast/Ten Speed Press)

"We have just fromed [sic] Tactical Studies Rules, and we wish to let the wargaming community know that a new line of miniature rules is available."

With this letter, written by Gary Gygax to wargaming zine publisher Jim Lurvey, one of the founders of what would become TSR, announced that a January 1974 release for Dungeons & Dragons was forthcoming. This, plus other evidence compiled by Jon Peterson (as pointed out by the Grognardia blog), points to the last Sunday of January 1974 as the best date for the "anniversary" of D&D. The first sale was in "late January 1974," Gygax later wrote, and on the last Sunday of January 1974, Gygax invited potential customers to drop by his house in the afternoon to try it out.

You could argue whether a final draft, printing, announcement, sale, or first session counts as the true "birth" of D&D, but we have to go with something, and Peterson's reasoning seems fairly sound. Gygax's memory, and a documented session at his own house, are a good point to pin down the celebration of this thing that has shaped a seemingly infinite number of other things.

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Tens of thousands of pregnancies from rape occurring in abortion-ban states

Par : Beth Mole
Pro-choice protesters march in Texas, carrying signs that say

Enlarge / Pro-choice protesters march outside the Texas State Capitol on Sept. 1, 2021, in Austin, Texas. (credit: Getty Images | The Washington Post )

Fourteen states have banned abortions at any gestational age since the Supreme Court overruled Roe v. Wade in 2022. Since the enactment of those abortion bans, an estimated 64,565 people became pregnant as a result of rape in those states. But, while five of the 14 states have exceptions for rape, all of the states logged only 10 or fewer legal abortions per month since their respective bans were enacted.

The finding, published this week in JAMA Internal Medicine, is a stark look at the effects of such bans on reproductive health care. The study did not assess how many of the estimated 64,565 pregnancies resulted in births, but it makes clear that tens of thousands of pregnant rape survivors, including children, were forced to turn to illegal procedures, self-managed abortions, or burdensome travel to states where abortion is legal—cost-prohibitive to many—as an alternative to carrying a rape-related pregnancy to term.

It also showed that legal exceptions for rape don't work. The states with those exceptions apply stringent time limits on the pregnancy and require victims to report their rapes to law enforcement, which likely disqualifies most. The US Department of Justice estimates that only 21 percent of victims report their rape to police, for myriad reasons.

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Following lawsuit, rep admits “AI” George Carlin was human-written

A promotional image cited in the lawsuit uses Carlin's name and image to promote the Dudsey podcast and special.

Enlarge / A promotional image cited in the lawsuit uses Carlin's name and image to promote the Dudsey podcast and special.

The estate of George Carlin has filed a federal lawsuit against the comedy podcast Dudesy for an hour-long comedy special sold as an AI-generated impression of the late comedian. But a representative for one of the podcast hosts behind the special now admits that it was actually written by a human.

In the lawsuit, filed by Carlin manager Jerold Hamza in a California district court, the Carlin estate points out that the special, "George Carlin: I'm Glad I'm Dead," (which was set to "private" on YouTube shortly after the lawsuit was filed) presents itself as being created by an AI trained on decades worth of Carlin's material. That training would, by definition, involve making "unauthorized copies" of "Carlin's original, copyrighted routines" without permission in order "to fabricate a semblance of Carlin’s voice and generate a Carlin stand-up comedy routine," according to the lawsuit.

"Defendants’ AI-generated 'George Carlin Special' is not a creative work," the lawsuit reads, in part. "It is a piece of computer-generated click-bait which detracts from the value of Carlin’s comedic works and harms his reputation. It is a casual theft of a great American artist’s work."

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PlayStation has blocked hardware cheating device Cronus Zen, others may follow

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Enlarge / Who doesn't want less recoil? Unless, that is, you're someone competing against the person getting this benefit with a $100 "emulation" device. (credit: Cronus)

The Cronus Zen describes itself as a hardware tool for "universal controller compatibility," letting you plug in a third-party controller, an Xbox controller into a PlayStation, or even your keyboard and mouse into a console. But you can also use its scripting engine to "amplify your game" and set up "GamePacks" to do things like reduce recoil animations in games like Call of Duty. And that is where Cronus seems to have gotten into trouble.

As first noted by the Call of Duty news channel CharlieIntel, the latest update to the PlayStation 5's system (24.01-08.60.00) software blocks the Cronus from connecting. The update is "NOT mandatory," Cronus claims in a notice on its website, so Zen players can hold off and keep playing. Still, there is "currently no timetable on a fix … it could be 24 (hours), 24 days, 24 months, we won't know until we've dug into it." There is, for now, a "Remote Play Workaround" for those already too far updated.

Ars attempted to reach Cronus for comment and reached out to Sony as well and will update this post with any new information.

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Did an AI write that hour-long “George Carlin” special? I’m not convinced.

"Well, we all have a face/That we hide away forever"

Enlarge / "Well, we all have a face/That we hide away forever" (credit: Aurich Lawson | Getty Images)

If you've paid any attention to the intersection of AI and culture this month, you’ve probably stumbled across a video billed as a “comedy AI” doing a 60-minute impression of a stand-up routine by the late, great George Carlin. Even if you didn’t watch “George Carlin: I’m Glad I’m Dead,” you probably stumbled on some of the many, many headlines suggesting that AI had brought the legendary comedian “back from the dead” in some sense.

Or maybe you saw some of the disgusted and/or panicked responses to the special among Carlin fans, comedy purists, and AI fearmongers. Those included Carlin’s daughter, Kelly, who told The Daily Beast that she’s talking to lawyers about the possibility of legal action against the special’s creators, the comedy podcast Dudesy.

But I think that anger is at least partially misplaced. After spending the last few weeks diving down a distractingly deep rabbit hole, I’m convinced that Dudesy’s “AI-generated” George Carlin special was actually written by a human, using voice- and image-generation tools to essentially perform in “AI face” as part of an ongoing comedy bit.

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Inside the making of National Geographic’s A Real Bug’s Life docuseries

closeup of a jumping spider

Enlarge / A bold jumping spider struggles to survive in New York City in A Real Bug's Life, narrated by Awkwafina. (credit: National Geographic/Jamie Thorpe)

Pixar's 1998 animated film A Bug's Life celebrated its 25th anniversary last year, and National Geographic decided to mark the occasion with a new science docuseries, A Real Bug's Life, narrated by Awkwafina. As with the Pixar film, the bugs (and adjacent creatures) are the main characters here, from cockroaches, monarch butterflies, and praying mantises to bees, spiders, and even hermit crabs. The 10 episodes tell their stories as they struggle to survive in their respective habitats, capturing entire ecosystems in the process: city streets, a farm, the rainforest, a Texas backyard, and the African savannah, for example.

The genesis for the docuseries lies in a rumored sequel to the original film. That inspired producer Bill Markham, among others, to pitch a documentary series on a real bug's life to National Geographic. "It was the quickest commission ever," Markham told Ars. "They said yes literally over a weekend. It was such a good idea, to film bugs in an entertaining family way with Pixar sensibilities." And thanks to the advent of new technologies, plus a couple of skilled "bug wranglers," the team captured the bug's-eye view of the world beautifully.

According to Director of Photography Nathan Small, long tube-like probe lenses enabled the camera crew to capture footage from inside tiny cracks and holes to better document the buggy behavior. They also made better use of macro lenses. "Before when we had macro lenses, they were all quite long, and the background would be really smooshy with everything out of focus," Small told Ars. "We tried to shoot everything from very low, very wide angles with lots of context, so you can experience the world from the point of view of the animal and see how it sits in its location, rather than just a smooshy background."

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Sierra Space is blowing up stuff to prove inflatable habitats are safe

Sierra Space's 300-cubic-meter inflatable habitat burst at 77 psi, five times the pressure it would need to handle in space.

Enlarge / Sierra Space's 300-cubic-meter inflatable habitat burst at 77 psi, five times the pressure it would need to handle in space. (credit: Sierra Space)

Sierra Space says it has demonstrated in a ground test that a full-scale inflatable habitat for a future space station can meet NASA's recommended safety standards, clearing a technical gate on the road toward building a commercial outpost in low-Earth orbit.

During a December test at NASA's Marshall Space Flight Center in Alabama, Sierra Space's 300 cubic meter inflatable structure withstood five times the pressure it would need to handle in space. The so-called ultimate burst pressure test was designed to measure the limits of the soft goods technology Sierra Space is developing alongside ILC Dover, which also built spacesuits for NASA.

The 27-foot-diameter (8.2-meter) inflatable structure burst at 77 psi, exceeding NASA's recommended safety standard of 60.8 psi, which is four times the module's real-life operating pressure at 15.2 psi.

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Big Pharma hiked the price of 775 drugs this year so far: Report

Par : Beth Mole
Sen. Bernie Sanders (I-Vermont).

Enlarge / Sen. Bernie Sanders (I-Vermont). (credit: Getty | Chip Somodevilla /)

Pharmaceutical companies have raised the list prices of 775 brand-name drugs so far this year, with a median increase of 4.5 percent, exceeding the rate of inflation, according to an analysis conducted for The Wall Street Journal.

Drugmakers typically raise prices at the start of the year, and Ars reported on January 2 that companies had plans to raise the list prices of more than 500 prescription medications. The updated analysis, carried out by 46brooklyn Research, a nonprofit drug-pricing analytics group, gives a clearer picture of pharmaceutical companies' activities this month.

High-profile drugs Ozempic (made by Novo Nordisk) and Mounjaro (Eli Lilly), both used for Type II diabetes and weight loss, were among those that saw price increases. Ozempic's list price went up 3.5 percent to nearly $970 for a month’s supply, while Mounjaro went up 4.5 percent to almost $1,070 a month. The annual inflation rate in the US was 3.4 percent for 2023.

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TSMC predicts delays, less advanced chips at second Arizona fab

US President Joe Biden speaks during a "First Tool-In" ceremony at the Taiwan Semiconductor Manufacturing Co. facility under construction in Phoenix, Arizona, US, on Tuesday, Dec. 6, 2022. TSMC today announced plans to boost its investment in the state to $40 billion and construct a second production facility, following major customers urging the Taiwanese chipmaker to build more advanced semiconductors in the US.

Enlarge / US President Joe Biden speaks during a "First Tool-In" ceremony at the Taiwan Semiconductor Manufacturing Co. facility under construction in Phoenix, Arizona, US, on Tuesday, Dec. 6, 2022. TSMC today announced plans to boost its investment in the state to $40 billion and construct a second production facility, following major customers urging the Taiwanese chipmaker to build more advanced semiconductors in the US. (credit: Bloomberg / Contributor | Bloomberg)

President Joe Biden's plan to expand America's command of the global chips market hit another setback Thursday when Taiwan Semiconductor Manufacturing Company (TSMC) Chairman Mark Liu announced that he anticipates significant delays at the company's second chips plant in Arizona.

This news follows previous delays announced last year at TSMC's first chips plant, which Liu partly blamed on US workers lacking specialized skills. At Thursday's news conference, Liu "reiterated" those complaints, Bloomberg reported, claiming that TSMC is still struggling to hire skilled workers in Arizona.

According to Liu, TSMC's second Arizona plant—which is supposed to become the most advanced facility in the US—likely won't start volume production of advanced chips until 2027 or 2028. That's potentially two years longer than initial projections suggesting that production would start in 2026.

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With fewer pollinators, plants are cutting back on nectar production

Image of a field of multi-colored flowers.

Enlarge (credit: Darrell Gulin)

In a striking experiment, scientists from the French Centre Nationale de la Recherche Scientifique (CNRS) and the University of Montpellier have observed the impact of selective pressure on a flowering plant. By comparing the pansy flower variety of today that grows in the Paris region to those regrown from the seeds of the same variety collected in the 1990s and 2000s, the researchers have observed notable differences.

According to the study’s co-author, Pierre-Oliver Cheptou, the plant’s evolution over this period has resulted in a 25 percent increase in self-pollination (or selfing) in modern two plants. “We also noticed a 10 percent decrease in the flower size and a 20 percent reduction in the nectar production, which suggests the decrease in rewards for pollinators such as bumblebees,” he said.

To confirm this outcome, Cheptou and his colleagues conducted behavioral tests involving bumblebees "which preferred the ancestor plants,” Cheptou said.

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COVID shots protect against COVID-related strokes, heart attacks, study finds

Par : Beth Mole
A vial of the updated 2023-2024 formula of Pfizer's COVID-19 vaccine at a CVS Pharmacy in Eagle Rock, California, on September 14, 2023.

Enlarge / A vial of the updated 2023-2024 formula of Pfizer's COVID-19 vaccine at a CVS Pharmacy in Eagle Rock, California, on September 14, 2023. (credit: Getty | Irfan Khan)

Staying up to date on COVID-19 vaccines can cut the risk of COVID-related strokes, blood clots, and heart attacks by around 50 percent in people ages 65 years or older and in those with a condition that makes them more vulnerable to those events, according to a new study from the Centers for Disease Control and Prevention.

The finding, published this week in the CDC's Morbidity and Mortality Weekly Report, should help ease concerns that the shots may conversely increase the risk of those events—collectively called thromboembolic events. In January 2023, the CDC and the Food and Drug Administration jointly reported a preliminary safety signal from their vaccine-monitoring systems that indicated mRNA COVID-19 vaccines may increase the risk of strokes in the 21 days after vaccination of people ages 65 and older. Since that initial report, that signal decreased, becoming statistically insignificant. Other vaccine monitoring systems, including international systems, have not picked up such a signal. Further studies (summarized here) have not produced clear or consistent data pointing to a link to strokes.

In May, the FDA concluded that the evidence does not support any safety concern and reported that "scientists believe factors other than vaccination might have contributed to the initial finding."

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I found David Lynch’s lost Dune II script

Par : WIRED
Kyle MacLachlan in Dune

Enlarge / Kyle MacLachlan in Dune, 1984. (credit: Everett)

David Lynch’s 1984 sci-fi epic Dune is—in many ways—a misbegotten botch job. Still, as with more than a few ineffectively ambitious films before it, the artistic flourishes Lynch grafted onto Frank Herbert’s sprawling Machiavellian narrative of warring space dynasties have earned it true cult classic status. Today, fans of the film, which earned a paltry $30 million at the box office and truly bruising reviews upon its release, still wonder what Lynch would have done if given the opportunity to adapt the next two novels in Herbert’s cycle: Dune Messiah and Children of Dune.

Franchising was the plan before the first film crashed and burned, with Lynch and star Kyle MacLachlan (playing Paul Atreides) set to shoot both Dune sequels back-to-back in 1986. Miniature spaceship models, costumes, and props from the first film were placed in storage by producer Dino De Laurentiis for use on these follow-ups, while the director hammered away on a Dune II script. “I wrote half a script for the second Dune. I really got into it because it wasn’t a big story,” he says in Lynch on Lynch, “more like a neighborhood story. It had some really cool things in it.”

During the two years I spent putting together my book A Masterpiece in Disarray: David Lynch’s Dune—An Oral History, I had no luck uncovering Lynch's script for Dune II, despite Frank Herbert telling Prevue magazine in December 1984 that he possessed a copy and was advising Lynch on it. “Now that we speak the same ‘language,’ it’s much easier for both of us to make progress, especially with the screenplays,” Herbert told the publication. Then, in July 2023, within the Frank Herbert archives at California State University, Fullerton, I came across a slim folder with a sticky note declaring “Dune Messiah script revisions,” addressed to the second floor of VFX man Barry Nolan’s office in Burbank where Lynch supervised the final effects shoots and editing on Dune.

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The key to fighting pseudoscience isn’t mockery—it’s empathy

The key to fighting pseudoscience isn’t mockery—it’s empathy

Enlarge (credit: Aurich Lawson | Getty Images)

As a scientist heavily engaged in science communication, I’ve seen it all.

People have come to my public talks to argue with me that the Big Bang never happened. People have sent me handwritten letters explaining how dark matter means that ghosts are real. People have asked me for my scientific opinion about homeopathy—and scoffed when they didn’t like my answer. People have told me, to my face, that what they just learned on a TV show proves that aliens built the pyramids and that I didn’t understand the science.

People have left comments on my YouTube videos saying… well, let’s not even go there.

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Canada vows to defend its drug supply against Florida importation plan

Par : Beth Mole
A Royal Canadian Mounted Police officer stands guard outside the Senate of Canada prior to the Speech from the Throne on September 23, 2020, in Ottawa.

Enlarge / A Royal Canadian Mounted Police officer stands guard outside the Senate of Canada prior to the Speech from the Throne on September 23, 2020, in Ottawa. (credit: Getty | DAVE CHAN/AFP)

Canada issued a warning Monday that it stands ready to defend its prescription drug supply from US importation plans—and also said the plans wouldn't work for the US, anyway. "Bulk importation will not provide an effective solution to the problem of high drug prices in the US," Health Canada said in a statement.

The defensive stance comes just days after the US Food and Drug Administration granted Florida authorization to directly import cheaper prescription drugs from Canada in an effort to help drag down America's uniquely stratospheric drug pricing. Florida is the first state to win such an authorization, and Florida Governor Ron DeSantis celebrated it, claiming the drug imports will save the state "up to $180 million in the first year alone." There are caveats, though. Before Florida can import any drugs, it must complete several obligations, including submitting to the FDA additional drug-specific information, testing the drugs for authenticity and FDA compliance, and relabeling them in accordance with FDA labeling.

The FDA authorized the importation program in accordance with section 804 of the Federal Food, Drug, and Cosmetic Act (FD&C Act). The move stems from President Biden’s "Executive Order on Promoting Competition in the American Economy," which directed the FDA to help develop such programs.

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Chromium found in lead-tainted fruit pouches may explain contamination

Par : Beth Mole
The three recalled pouches linked to lead poisonings.

Enlarge / The three recalled pouches linked to lead poisonings. (credit: FDA)

The Food and Drug Administration has discovered a second metal contaminant—chromium—in the recalled cinnamon applesauce pouches found to contain cinnamon contaminated with extremely high levels of lead. The products have now poisoned nearly 300 young children in 37 states.

The health implications of the additional contaminant are not clear. There is no antidote for chromium exposure, and the Centers for Disease Control and Prevention recommends supportive care. But the finding does hint at the possible motivation behind the tragic poisonings.

In the FDA's announcement, the agency noted that "The lead-to-chromium ratio in the cinnamon apple puree sample is consistent with that of lead chromate (PbCrO4)." This is a notorious adulterant of spices used to artificially bolster their color and weight.

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A complete (so far) Star Citizen ship collection now costs $48,000

There aren't many online game stores where you can spend $48,000 on a single "Add to Cart."

Enlarge / There aren't many online game stores where you can spend $48,000 on a single "Add to Cart." (credit: RSI)

At this point, over 11 years after we first wrote about Star Citizen, the still-in-alpha game is interesting less as something that might eventually be "finished" and more as a fascinating tale of feature creep and fundraising success. To that last point, we were suitably boggled at the recent news that Roberts Space Industries is now offering a  $48,000 "Legatus Pack" as a "perfect collection" of "all ships released and concepted through [in-universe year] 2953."

The collection of 187 ships (and hundreds of accessories like paint colors, skins, armor, and in-game posters) is now roughly two-thirds of the median annual household income in the US (circa 2022). But that price isn't even available to lookie-loos like you and me; to add the package to an online shopping cart, you must first spend at least $1,000 to become a member of the game's Chairman's Club.

What a bargain!

While the newest Legatus Pack launched in late December, the offering isn't a new concept for developer Roberts Space Industries. The first Legatus Pack launched in May 2018 for a relatively reasonable $27,000. Before that, similar "Completionist" packs of all in-game content released up to that point would run players up to $15,000.

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Pornhub pulls out of Montana, NC as age-verification battle rages on

Pornhub pulls out of Montana, NC as age-verification battle rages on

Enlarge (credit: Dmitry Mayer | iStock / Getty Images Plus)

To kick off the new year, Montana and North Carolina joined a growing number of states enforcing laws requiring age verification to access adult content online.

In the days before the laws took effect on January 1, Aylo—the owner of adult sites like Pornhub, Youporn, Brazzers, and Redtube—blocked access for users in both states, continuing to argue that requiring ID for every login makes adult sites less safe for everyone.

“As you may know, your elected officials in your state are requiring us to verify your age before allowing you access to our website," adult entertainer Cherie DeVille said in a public service announcement displayed to users attempting to access sites in Montana and North Carolina. "While safety and compliance are at the forefront of our mission, giving your ID card every time you want to visit an adult platform is not the most effective solution for protecting our users, and in fact, will put children and your privacy at risk.”

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Big Pharma to raise US list prices of 500 drugs in January: Report

Par : Beth Mole
Hundred dollar bills inside prescription pill bottles

Enlarge (credit: Getty | Bill Diodato)

January is usually a big month for hiking the list prices of drugs in the US—and it looks like 2024 will be no different. Pharmaceutical companies plan to raise the US list prices of more than 500 prescription medications this month, and more are expected to be announced in the coming weeks. That's according to a report from Reuters, which is based on data from the health care research firm 3 Axis Advisors.

The high-profile drug makers with plans to increase prices include giants such as Pfizer, Sanofi, and Takeda.

This year's tally of 500 is in line with the past few years, with 452 list price increases as of January 1, 2023, and a high of 602 on January 1, 2021, according to data from 46brooklyn, a drug pricing nonprofit related to 3 Axis Advisors. Overall, drug makers raised the list prices of 1,425 drugs in 2023, down slightly from 1,460 in 2022.

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Here’s how an off-road racing series will make its own hydrogen fuel

DECEMBER 03: Lia Block (USA) / Timo Scheider (DEU), Carl Cox Motorsport, battles with Amanda Sorensen (USA) / RJ Anderson (USA), GMC Hummer EV Chip Ganassi Racing during the Copper X-Prix, Chile on December 03, 2023. (Photo by Colin McMaster / LAT Images)

Enlarge / Extreme E travels to remote locations by boat and brings its own energy infrastructure with it. Currently, it makes its own hydrogen on site and uses that to charge EV batteries, but in 2025, the cars will switch to hydrogen fuel cells. (credit: Colin McMaster / LAT Images)

ANTOFAGASTA, Chile — On a picnic bench in Chile's Atacama Desert, one of the most remote locations on Earth, Alejandro Agag is holding court.

"Welcome to the edge of the world," he laughs, gesturing toward the vast desert around him. A gust of wind kicks a cloud of sand and dust across the table. "It's amazing, this place."

The 53-year-old Spanish entrepreneur is taking in the sights and sounds of the season 3 finale of Extreme E, the off-road electric racing series he launched in 2021. Part of the series' ethos is that it races exclusively in regions of the globe that are heavily impacted by climate change (such as the Atacama Desert—the driest, non-polar region on Earth), typically with no spectators present.

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X-ray imaging of The Night Watch reveals previously unknown lead layer

The Nightwatch, or Militia Company of District II under the Command of Captain Frans Banninck Cocq (1642)

Enlarge / Rembrandt's The Night Watch underwent many chemical and mechanical alterations over the last 400 years. (credit: Public domain)

Rembrandt's The Night Watch, painted in 1642, is the Dutch master's largest surviving painting, known particularly for its exquisite use of light and shadow. A new X-ray imaging analysis of the masterpiece has revealed an unexpected lead layer, perhaps applied as a protective measure while preparing the canvas, according to a new paper published in the journal Science Advances. The work was part of the Rijksmuseum's ongoing Operation Night Watch, the largest multidisciplinary research and conservation project for Rembrandt's famous painting, devoted to its long-term preservation.

The famous scene depicted in The Night Watch—officially called Militia Company of District II under the Command of Captain Frans Banninck Cocq—was not meant to have taken place at night. Rather, the dark appearance is the result of the accumulation of dirt and varnish over four centuries, as the painting was subject to various kinds of chemical and mechanical alterations.

For instance, in 1715, The Night Watch was moved to Amsterdam’s City Hall (now the Royal Palace on Dam Square). It was too large for the new location, so the painting was trimmed on all four sides, and the trimmed pieces were never found (although in 2021, AI was used to re-create the original full painting). The objective of Operation Night Watch is to employ a wide variety of imaging and analytical techniques to better understand the materials Rembrandt used to create his masterpiece and how those materials have changed over time.

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Twitch quickly reverses policy that “went too far” allowing nudity

Twitch quickly reverses policy that “went too far” allowing nudity

Enlarge (credit: SOPA Images / Contributor | LightRocket)

Just two days after updating its policy to allow for more nudity, Twitch has announced that it's immediately "rolling back the artistic nudity changes."

"Moving forward, depictions of real or fictional nudity won’t be allowed on Twitch, regardless of the medium," Twitch CEO Dan Clancy wrote in a blog post on Friday.

Clancy explained the decision to reverse course, writing that the policy was updated in response to user requests that Twitch "allow the thriving artist community on Twitch to utilize the human form in their art."

However, soon after the policy was changed, Clancy said that an unquantified number of streamers "created content that was in violation of our new policy." Twitch also received complaints about other uploaded content "that was allowed under the updated policy" but sparked concerns that Twitch shared.

"Upon reflection, we have decided that we went too far with this change," Clancy wrote. "Digital depictions of nudity present a unique challenge—AI can be used to create realistic images, and it can be hard to distinguish between digital art and photography."

Clancy confirmed that there are currently no other changes to the sexual content policy recently announced that briefly allowed more nudity after years of banning mostly female-presenting streamers who were penalized for violating sexual content policies that Twitch now admits were too confusing.

In one prominent example, just two days before the policy change, Twitch banned OnlyFans model Morgpie for posting "topless" streams. Although Morgpie's videos were shot to imply nudity, they "never actually showed content that explicitly violated Twitch’s sexual content policies," TechCrunch reported. To critics, Twitch's rationale for banning Morgpie remains unclear.

In a blog post on Wednesday, Twitch Chief Customer Trust Officer Angela Hession wrote that Twitch "received consistent feedback from streamers that our current policies around sexual content are confusing and that it can be difficult to know how their content will be interpreted based on these policies."

Hession confirmed that Twitch's policy prohibiting "content that ‘deliberately highlighted breasts, buttocks or pelvic region,’ even when fully clothed" was confusing.

"Streamers found it difficult to determine what was prohibited and what was allowed and often evaluating whether or not a stream violated this portion of the policy was subjective," Hession wrote.

Combined with another policy that restricted "sexually suggestive" content, Twitch's former policy was found to be "overly punitive" and "resulted in female-presenting streamers being disproportionately penalized," Hession wrote.

In an effort to eliminate confusion, Twitch announced that it had consolidated two separate policies that addressed sexual content under Twitch's community guidelines into one single sexual content policy. That policy "specifies the types of sexual content that are prohibited on Twitch" and clarifies enforcement.

Another key part of the policy overhaul, Twitch has also begun allowing some sexual content that was previously restricted, so long as appropriate Content Classification Labels (CCLs) indicating sexual themes are applied.

Now, labeled content is allowed that features "body writing on female-presenting breasts and/or buttocks regardless of gender" and "erotic dances that involve disrobing or disrobing gestures, such as strip teases."

These labels will ensure that content is not removed but also prevent mature content from being promoted on the homepage, Hession wrote, ensuring that no Twitch user ever encounters inappropriate content that they do not wish to see. The only exceptions will be made for streams labeled as including mature-rated games and profanity, which will still appear in the main feed on the homepage. Streams with sexual themes label will, however, still be recommended in the left bar of the homepage, where a thumbnail isn't displayed.

"We believe that accurate content labeling is key to helping viewers get the experience they expect, and now that we can enable appropriate labeling of sexual content using CCLs we believe that some of the restrictions in our former policies are no longer required," Hession wrote. "In addition to providing clarity, these updates will also reduce the risk of inconsistent enforcement and bring our policy more in line with other social media services."

Failing to label sexual content can result in penalties, like warnings, but not suspensions, Hession wrote. Twitch will automatically apply labels to sexual content missing labels, and any repeated failure to label content could result in a label "temporarily locked onto the stream."

In addition to real and fictional nudity, some other sexual content is still prohibited, including pornographic content, youth nudity, "fictionalized sexual acts or masturbation," and "simulated sexual activity or erotic roleplay with other players in online games." Uploading such prohibited content can result in content removals or account suspensions. A complete overview of what's still banned can be found here.

Clancy wrote that Twitch is now "in the process of pushing out updates" to its community guidelines that reflect the latest changes to the sexual content policy.

"While I wish we would have predicted this outcome, part of our job is to make adjustments that serve the community," Clancy wrote. "I apologize for the confusion that this update has caused."

This story was updated on December 15 to reflect changes to Twitch's policy.

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The future of Arrakis is at stake in latest trailer for Dune: Part Two

Dune: Part Two is the next chapter in director Denis Villeneuve's adaptation of Frank Herbert’s celebrated novel.

We didn't get to see Dune: Part Two—the second film in director Denis Villeneuve's stunning adaptation of Frank Herbert's sci-fi classic—last month as originally planned since the film's November release was delayed until next March due to the Hollywood strikes. But Warner Bros. doesn't want us to completely forget about Dune in the meantime, so it dropped another trailer for the holiday season.

(Spoilers for Dune: Part One below.)

As reported previously (also here and here), Herbert's novel Dune is set in the distant future and follows the fortunes of various noble houses in what amounts to a feudal interstellar society. Much of the action takes place on the planet Arrakis, where the economy is driven largely by a rare, life-extending drug called melange ("the spice"). Melange also conveys a kind of prescience and makes faster-than-light travel practical. There's betrayal, a prophecy concerning a messianic figure, giant sandworms, and battle upon battle as protagonist Paul Atreides (Timothée Chalamet) contends with rival House Harkonnen and strives to defeat the forces of Shaddam IV, Emperor of the Known Universe.

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Here’s how Ducati made its motorbikes reliable under VW Group

In the past you needed to be brave to own an Italian motorcycle. Now you just need to be brave to ride one.

Enlarge / In the past you needed to be brave to own an Italian motorcycle. Now you just need to be brave to ride one. (credit: Ducati)

BOLOGNA, ITALY—For decades, owning an Italian motorcycle required a tradeoff. On one hand, Italian bikemakers led the pack with gorgeous designs and the most exotic, highest-performing engines in the world. No other country could come close to matching the sounds and smells of a Ducati, Moto Guzzi, or Aprilia revving by. But build quality and reliability always presented a challenge for owners, not to mention parts availability and exorbitant maintenance costs.

Ducati arguably led the charge in every regard, setting a standard as the Ferrari of the motorcycle world with eye-catching Rosso Corsa red paint jobs to go along with real racing success in MotoGP and World Superbike thanks to famous—some might say infamous—desmodromic engines. However, In recent years under Volkswagen Group's ownership, Ducati has made great strides in reliability and build quality, which explains to a large extent why 2022 was the firm's most profitable year ever, with 62,000 bikes sold worldwide.

During a recent trip to Italy, I visited the Ducati factory in Bologna to learn how modernizing the production facility at Borgo Panigale helped improve the bikes built there over the decade since joining the Volkswagen group.

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