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COVID-19 made the weaknesses in our pandemic preparedness at national and global levels painfully clear. But a new study highlights that even at the first, local steps of an outbreak with pandemic-potential, we are worryingly underprepared.
Health officials in New York set up a regional test of healthcare facilities to identify and respond to a patient with a mystery infection that could pose a pandemic-level threat. But things didn't go well. Overall, responses were slow, appropriate use of personal protective equipment was spotty, and only 60 percent of facilities passed the basics of the test—an overall failing grade.
"These drills identified needs for health care workers and health care facility staff member training to achieve earlier identification, masking, and isolation of potentially infectious febrile patients," the officials wrote in the study, which was published in the Morbidity and Mortality Weekly Report.
Labor Day is in the rearview mirror, kids are back to school, and a squall of pumpkin spice is upon us. It's that time again to prepare for the equally inevitable respiratory virus season with annual vaccines.
With fervent anti-vaccine activist Robert F. Kennedy Jr. as the country's top health official, it might seem like the rollout of this year's shots could be a disaster. For instance, one of Kennedy's first actions as health secretary last year was to obliterate an ad campaign for flu shots amid a particularly deadly flu season. As we head into this fall, the Centers for Disease Control and Prevention's vaccine advisory committee—which normally sets vaccination recommendations and insurance coverage for the shots—is nonfunctioning. A federal judge ruled in March that the anti-vaccine allies Kennedy installed on the panel were illegally appointed and unfit to serve. All their changes to vaccine policy have been temporarily voided. And meanwhile, Kennedy spent last week trying to obscure the number of babies who died from measles so far this year (it was two, including a newborn).
Despite all of that, the fall vaccine effort is looking like it will likely be somewhat smooth, potentially unremarkable even. The Food and Drug Administration has approved updated flu and COVID-19 shots for this season. Those shots have already begun arriving at pharmacies—in case your pharmacy hasn't already sent you multiple texts and reminders. While there are still some snags for access, it seems like it will be a lot like last year's fall vaccine rollout.
Fashionistas of a certain age no doubt remember the late designer Stephen Sprouse, who gave Blondie's Debbie Harry her distinctive Bowery punk style. Sprouse's first collections in the mid-1980s made a major splash, melding graffiti prints, a playful '60s aesthetic, and bright Day-Glo colors that won admirers such as Andy Warhol.
Several examples of Sprouse's work are preserved in the textiles collection of the Indianapolis Museum of Art at Newfields, where conservationists are trying to learn more about the phosphorescent and fluorescent pigments the designer used in his creations in order to keep the colors from dulling over time. They described recent advances in that research at a meeting of the American Chemical Society (ACS) held this week in Chicago.
Scientists began describing minerals that glowed in the dark as phosphors in the Middle Ages. Typically, such materials take on a charge when exposed to light, storing the absorbed energy and releasing it gradually as re-emitted light. Henri Becquerel discovered radioactive decay in 1896 because of his work with phosphorescent uranium salts: He left the salts in a closed drawer with photographic plates, which fogged up even without a light source. DayGlo paints and similar materials exploit the related phenomenon of fluorescence. DayGlo pigments fluoresce in daylight by essentially converting UV light into visible light to produce brighter, more vibrant colors.
Despite significant drama from Trump officials this year, the Food and Drug Administration has for the first time approved a flu vaccine that uses mRNA technology.
On Thursday, vaccine maker Moderna announced that its flu shot, mRNA-1010, aka mFLUSIVA, had earned approval for use in all adults ages 50 and up. The approval announcement follows a unanimous vote by FDA advisors in June to approve the vaccine. That vote was based on its superior efficacy to existing seasonal flu shots and a good safety record demonstrated in trials that included nearly 44,000 people. After that vote, the FDA set a goal of August 5 for a decision on the vaccine's fate.
While the unanimous support from FDA advisors boded well for Moderna's shot, the overall path to approval was treacherous and uncertain, even until the end. For one thing, current Health Secretary Robert F. Kennedy Jr. is a well-established anti-vaccine advocate who has worked diligently in his time in office to thwart vaccinations. One of his first acts as health secretary was canceling a federal campaign to encourage people to get flu shots in the midst of a bad flu season—despite the fact that the Centers for Disease Control and Prevention had already paid for the campaign and the flu season was killing relatively high numbers of children.
Watering your lawn in the summer can be both pragmatic and fun with so-called "silly sprinklers," designed to create amusing loops and spirals of water jets. And there's some fascinating physics at work to boot. Researchers at New York University's Courant Institute conducted a series of experiments with different silly sprinkler designs to find the answer to a longstanding problem in fluid dynamics, according to a new paper published in the Proceedings of the National Academy of Sciences.
As previously reported, the reverse sprinkler problem is associated with physicist Richard Feynman because he popularized the concept, but it actually dates back to a chapter in Ernst Mach’s 1883 textbook The Science of Mechanics (Die Mechanik in Ihrer Entwicklung Historisch-Kritisch Dargerstellt). Mach’s thought experiment languished in relative obscurity until a group of Princeton University physicists began debating the issue in the 1940s.
Feynman was a graduate student there at the time and threw himself into the debate with gusto, even devising an experiment in the cyclotron laboratory to test his hypothesis. One might intuit that a reverse sprinkler would work just like a regular sprinkler, merely played backward, so to speak. But the physics turns out to be more complicated. “The answer is perfectly clear at first sight,” Feynman wrote in Surely You’re Joking, Mr. Feynman (1985). “The trouble was, some guy would think it was perfectly clear [that the rotation would be] one way, and another guy would think it was perfectly clear the other way.”
The Army, Navy, and Air Force are once again requiring basic trainees to get vaccinated against influenza after the virus quickly swept through an Air Force base in Texas, sickening at least 222 recruits and hospitalizing four.
The outbreak flared just two months after Defense Secretary Pete Hegseth abandoned a decades-long requirement for flu shots. The requirement was intended to keep armed forces healthy in their bases, which provide ideally tight conditions for a variety of pathogens, including influenza, to run rampant. Mandates stem from centuries of intertwining histories of militaries, war, and human pathogens that have firmly established the danger that infectious diseases pose to armed forces.
But in April, Hegseth claimed that flu shot requirements were "not rational" and said removing the requirement was "restoring freedom" to military members.
At a star-studded event that closed downtown Los Angeles' Sixth Street Viaduct last night, Mercedes and AMG unveiled the next generation of performance electric vehicles. The new four-door GT Coupe arrives in the midst of a pivotal period, the result of an almost experimental process that seems to take two steps forward and one step back quite regularly. In many ways, the all-electric AMG leaves previous plans in the past by effectively bringing the record-setting Concept AMG GT XX to series production, with many firsts for Mercedes supporting the abandonment of internal combustion power, including new axial motors from YASA and F1-derived battery cells.
Fittingly, then, Mercedes brought out its F1 team’s personnel, as George Russell presented the new car while Toto Wolff and Kimi Antonelli watched from the makeshift grandstands. Hollywood celebs ran the gamut, from Brad Pitt—who drove one GT onto the bridge—to Jacob Elordi and Kevin Hart, while Blink 182 played a surprisingly sarcastic mini set. All of the above may mean less to potential GT buyers than performance metrics and pricing when the 2027 model year comes along, but it only serves to prove just how big a deal Mercedes-AMG believes this will be.
In person, the new GT bears almost no resemblance to any of Benz’s prior EVs. No more bulbous, nautical EQS shapes or minorly smoothed over boxy G-Wagen aesthetic. The new design is more aided by digital renderings and iterative algorithms, especially the jutting front grille, reclined headlights, and Kamm-tail rear end—a bit of Aston Martin fore and aft. From the profile view, the proportions fit somewhere between a Porsche Panamera or Taycan, low-slung and slippery for ideal aerodynamic efficiency.
More and more routine vaccines are being linked to lower risks of dementia. Shots against seasonal flu, RSV, tetanus, diphtheria, and pertussis (Tdap), pneumococcal infections, hepatitis A and B, and typhoid have all been linked to lower risks. And one of the strongest connections is from vaccination against shingles, with more data supporting the link still coming in. But as the evidence mounts, scientists continue to puzzle over the pleasant surprise—how are vaccines that target specific pathogens inadvertently shielding our minds from deterioration?
A burgeoning hypothesis offers a brow-raising possibility: The shots may be protecting our noggins by training the part of our immune system that had long been considered untrainable. If the idea holds up, it could generate a deeper understanding of fundamental aspects of our immune systems while opening new avenues to treating or preventing dementia. It could also add another dimension to the benefits of vaccines, which already save millions of lives worldwide.
It's well understood how vaccines work generally; they're designed to prime our immune systems against specific pathogens. Vaccines present either defanged pathogens or distinctive fragments of them to specialized immune cells—namely, T cells and antibody-producing B cells—that can then learn to identify those microbial enemies.
A little over a year ago, MG was leading the relatively normal life of a twentysomething in Scottsdale, Arizona. She worked as a personal assistant and supplemented her income by waiting tables on the weekends. Like most women her age, she had an Instagram account, where she’d occasionally post Stories and photos of herself getting matcha and hanging out by the pool with her friends, or going to Pilates.
“I never really cared to pop off and become popular on social media,” says MG (who is cited only as MG in the lawsuit to protect her identity). “I just used it the way most people did when it first came out, to share their lives with the people closest to them.” She has a little more than 9,000 followers—a robust following, but nowhere close to a massive platform.
Last summer, she received a DM from one of her followers. Did she know, the person asked her, that photos and videos of a woman who looked exactly like MG were circulating on Instagram? MG clicked the link and saw multiple Reels of what appeared to be her face superimposed onto a body that looked exactly like her own. The woman in the photo was scantily clad, with tattoos in the same places as MG.
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